Samuel Polio, PhD

Dr. Samuel Polio uses his deep expertise and skills as a trained scientist to help directly translate discoveries into real-world applications to provide intellectual property protection to the Firm’s life sciences clients.

Prior to joining Choate, Samuel was a postdoctoral fellow in the Parameswaran Lab at Northeastern University in the Bioengineering Department studying asthma pathogenesis from the perspective of cell-extracellular matrix interactions. Samuel also was a postdoctoral fellow in the Peyton Lab at the University of Massachusetts Amherst, where he worked to develop a bio-mechanical hydrogel to mimic lung tissue for understanding breast cancer metastasis. Samuel received the 2018 Alpha Fund Award from Northeastern University for the co-development of a cell and tissue stretching device.

While receiving his PhD, Samuel developed a novel technique using microfabrication and soft lithography to pattern <2µm features for use in the measurement of cellular traction forces. During his undergraduate education, he was a researcher at in the TIME Lab at the Brigham and Women’s Hospital.

Publications and Presentations

  • “Comparative Mechanics of Lung Parenchyma,” co-author, PLOS One, 2018
  • “Topographical control of multiple cell adhesion ligands for traction force microscopy,” co-author, Integrative Biology 6(3):357-65
  • “A micropatterning and image processing approach to simplify measurement of cellular traction forces,” co-author, Acta Biomaterialia 8(1):82-88
  • “Bio-printing of collagen and VEGF –releasing fibrin gel scaffolds for neural stem cell culture,” co-author, Experimental Neurology 223(2):645-652

Education & Credentials

Boston University
PhD, 2014
Biomedical Engineering
Boston University
BS, 2009
Biomedical engineering

Admissions

U.S. Patent & Trademark Office